Neuropsychology Neuroimaging Lab

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Sterling C. Johnson PhD
 
 
 
 
s. johnson
Associate Professor of Medicine
Office location: D4225 GRECC
William S. Middleton VA Hospital
2500 Overlook Terrace (11G)
Madison, WI, 53705
Office Phone: (608) 256-1901 X 11946
Lab Phone: (608) 256-1901 X 12920
Fax: (608) 280-7165
Email: scj@medicine.wisc.edu

 

Research Activities: In my lab we use brain imaging in conjunction with neuropsychological measurement to study cognitive disorders of memory and self-awareness.  The lab seeks to address questions such as: How early in life does Alzheimer Disease begin and can functional imaging provide new knowledge about presymptomatic disease progression?  What are the neural substrates of awareness (or unawareness) of deficit in AD and other cognitive disoders? To answer questions like these we collaborate with a talented multi-disciplinary team, and study healthy volunteers across the age spectrum with and without risk factors for dementia, patients with Alzheimer's disease, Mild Cognitive Impairment, frontal temporal dementias, and patients with traumatic brain injury.


I'm Assistant Professor in the School of Medicine and Public Health. My primary appointment is in the Section of Geriatrics in the Department of Medicine and I am affiliated with the following  departments and centers on campus at the University of Wisconsin-Madison:

Department of Psychology
Wisconsin Comprehensive Memory Program
Neuroscience Training Program
Madison Veterans Hospital
Wisconsin Alzheimer's Institute
Wisconsin Institute on Aging
Wisconsin National Primate Research Center

Representative Publications

2007

Johnson SC, Ries, ML, Hess T, Carlsson CM, Gleason CE, Alexander AL, Rowley HA, Asthana S, Sager MA (in press).  Alzheimer Disease Risk in Healthy Middle-Aged Adults Affects Brain Function During Self Appraisal.  Archives of General Psychiatry.

Ries ML, Torgerson BM, Schmitz TW, Trivedi MA, Gleason CE, Carlsson CM, Rowley HA, Asthana A, Johnson SC (2007).  Anosognosia in mild cognitive impairment: Relationship to activation of cortical midline structures involved in self-appraisal. Journal of the International Neuropsychological Society, 13, 450-461. [pubmed]

Schmitz, TW, Johnson, SC (2007).  Relevance to the self: A brief review and framework of neural systems underlying appraisal.  Neuroscience and Biobehavioral Reviews, 31, 585-596. [pubmed]

Newman LM, Trivedi MA, Ries ML, Bendlin BB, Johnson SC (in press).  The Relationship Between Gray Matter Morphometry and Performance on Neuropsychological Tests of Frontal Lobe Function in a Large Sample of Cognitively Healthy Adults.  Brain Imaging and Behavior.

Johnson SC, Schmitz TW, Trivedi MA, Ries ML, Torgerson BM, Carlsson CM, Asthana S, Hermann, BP, Sager, MA (2006). The Influence of AD Family History and APOE4 on Mesial Temporal Lobe Activation. Journal of Neuroscience, 26, 6069-6076. [free at J Neurosci ]

2006

Johnson, SC, Schmitz, TW, Moritz, CH, Meyerand, ME, Rowley, HA, Alexander, AL, Hansen, KW, Gleason, CE, Carlsson, CM, Ries, ML, Asthana, S, Chen, K, Reiman, EM, Alexander, GE (2006). Activation of Brain Regions Vulnerable to Alzheimer’s Disease: The Effect of Mild Cognitive Impairment.  Neurobiology of Aging, 27, 1604-1612. [pubmed]

  Schmitz, TW, Johnson, SC. (2006). Self-appraisal decisions evoke dissociated dorsal—ventral aMPFC networks. Neuroimage, 30, 1050-1058.  [pubmed]

   Thottakara, P, Lazar, M, Johnson, SC, Alexander, AL (2006). Brodmann’s areas template for ROI selection in white matter tractography studies. Neuroimage, 29, 868-878.   [pubmed

2005

Johnson SC, Schmitz TW, Rowley HA, Alexander AL, Lee J, Davidson RJ. (2005). The cerebral response during subjective choice with and without self-reference. J Cogn Neurosci, 17(12), 1897-1906. [pubmed

Ward, MA, Carlsson, CM, Trivedi, MA, Sager, MA, Johnson, SC (2005).  The effect of body mass index on global brain volume in middle-aged adults:  a cross-sectional study.  BMC Neurology, 5:23 a [pubmed]  open access
Hua LH, Strigo IA, Baxter LC, Johnson SC, Craig AD. Antero-posterior somatotopy of innocuous cooling activation focus in human dorsal posterior insular cortex. Am J Physiology, 289:R319 - R325. 2005. [pubmed]

 

2004 and earlier

 

McMillan AB, Hermann BP, Johnson SC, Hansen RR, Seidenberg M, Meyerand ME. Voxel-based Morphometry of Unilateral Temporal Lobe Epilepsy Reveals Abnormalities in Cerebral White Matter. Neuroimage, 23:167-174, 2004.   [pubmed]

 

Schmitz TW, Kawahara-Baccus TN, Johnson SC. Metacognition, Self-reflection, and the Right Prefrontal Cortex. Neuroimage, 22:941-947, 2004.   [pubmed]

 

Johnson SC, Baxter, LC, Susskind-Wilder L, Connor DJ, Sabbagh MN, Caselli RJ. Hippocampal adaptation to face repetition in healthy elderly and mild cognitive impairment. Neuropsychologia, 42:980-989, 2004 [pubmed]

 

Baxter LC, Caselli RJ, Johnson SC, Reiman EM, Osborne D. Apolipoprotein E ε4 affects new learning in cognitively normal individuals at risk for Alzheimer’s Disease. Neurobiol Aging 24:947-952, 2003.   [pubmed]

 

Johnson SC, Baxter LC, Susskind-Wilder L, Pipe JG, Heiserman JE, Prigatano GP, Neural substrates of self-reflective thought. Brain, 125:1808-1814, 2002.     [pubmed] free open access a

 
 
 

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