Luigi Puglielli

Associate Professor


Dr. Puglielli’s broad research interests focus on the role that lipid metabolism plays in the regulation of Aβ (amyloid β-peptide) generation and synaptogenesis during both normal aging of the brain and the Alzheimer-type of neurodegeneration. Specifically, we focus on the role played by the ceramide-dependent signaling cascade, and by intracellular cholesterol distribution.